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Inventi Impact: Ethnopharmacology

Articles

  • Inventi:pep/25584/18
    The Anti-Inflammatory Effect of Fructus Kochiae on Allergic Contact Dermatitis Rats via\npERK1/2/TLR4/NF- B Pathway Activation
    01-Jan-1970 Research 2018 : April - June
    Zuoqi Xiao, Suxi Xiao, Yongning Zhang, Tao Pan, Bo Ouyang

    Allergic contact dermatitis (ACD) is a common irritability skin disease, which can be cured by using the Chinese patent medicine.\nTo explore the pharmacological effect of total flavonoids of FructusKochiae (FK) onACD,we used dinitrochlorobenzene- (DNCB-)\ninducedACDrats. Five groupswere used in our experiments.Thenormal group and theDNCB groupwere treatedwith 0.5%CMCNa;\nthe DNCB + hFK group was treated with a high dose of total flavonoids of FK (200mg/kg); the DNCB + lFK group was treated\nwith a low dose of FK (100mg/kg); the DNCB + Pre group was treated with prednisolone acetate (2.5mg/kg). The results showed\nthat FK treatment had significantly attenuated the inflammation induced by DNCB. The increased concentration of cytokines\nincluding IL-6, IL-18, and IFN-

    How to Cite this Article
    CC Compliant Citation: Zuoqi Xiao, Suxi Xiao, Yongning Zhang, Tao Pan, and Bo Ouyang, â??The Anti-Inflammatory Effect of Fructus\nKochiae on Allergic Contact Dermatitis Rats via pERK1/2/TLR4/NF-B Pathway Activation,â? Evidence-Based Complementary and\nAlternative Medicine, vol. 2018, Article ID 1096920, 12 pages, 2018. doi:10.1155/2018/1096920, https://creativecommons.org/\nlicenses/by/4.0/.
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